16-Day Inca & Panama Canal Discovery: Lima Overnight

Fort Lauderdale is South Florida's reinvented waterfront city, where three hundred miles of inland waterways, the NSU Art Museum's contemporary collection, and the tree-lined Las Olas Boulevard create a cruise departure point of genuine sophistication at Port Everglades. Arrive a day early between November and April to explore the 'Venice of America' by water taxi and discover the dining scene that has replaced Spring Break with year-round culinary ambition.

George Town, the capital of the Cayman Islands, is a vibrant port known for its rich history and diverse culinary scene. Must-do experiences include savoring local delicacies like conch fritters and exploring nearby attractions such as Cayman Brac and Little Cayman. The best season to visit is during the winter months, when the weather is pleasantly warm and ideal for outdoor adventures.

Fuerte Amador is Panama City's cruise gateway on the Pacific entrance to the Panama Canal, offering front-row views of the world's most important shipping lane and access to the UNESCO-listed Casco Viejo old quarter. Must-do experiences include watching ships transit the Miraflores Locks, exploring colonial plazas, and tasting ceviche at the Mercado de Mariscos. December through April's dry season offers the most pleasant weather.

Manta, Ecuador is a distinctive port city where deep cultural heritage meets authentic local atmosphere, featured on itineraries by Norwegian Cruise Line. Must-do experiences include exploring the vibrant local markets for regional specialties and fresh seafood, and discovering the waterfront quarter where maritime heritage meets contemporary energy. The optimal time to visit is November through April, when dry season brings clear skies and calm seas.

Salaverry is the Peruvian port gateway to Chan Chan — the largest pre-Columbian adobe city in South America — and the polychrome Moche temples that together create one of the Western Hemisphere's richest archaeological landscapes. Must-dos include the carved friezes of Chan Chan's Tschudi Complex, the vivid murals at Huaca de la Luna, and ceviche at colonial Trujillo's Plaza de Armas. Visit year-round; the coast is dry, with June through September best for archaeological site visits.

Callao, Peru, delivers South America's irresistible combination of dramatic landscapes, vibrant culture, and extraordinary biodiversity. Essential experiences include exploring local markets, tasting the distinctive regional cuisine, and venturing into the surrounding natural environments. Best visited May through September, when drier conditions prevail and temperatures remain pleasant. Cruise lines including Cunard feature this port on their most compelling itineraries. Whether you have a few hours or a full day, the port rewards exploration at every pace and in every direction.

General San Martín, in Peru's Paracas region, is the gateway to the wildlife-rich Islas Ballestas, the dramatic Paracas National Reserve, and the pisco bodegas of the Ica Valley where Peru's celebrated grape brandy originates. Must-dos include boat tours among sea lions and Humboldt penguins, viewing the mysterious Candelabra geoglyph, and tasting fresh ceviche with artisanal pisco. The Southern Hemisphere summer from December through March offers the best conditions.

Coquimbo is a Pacific port in Chile's Norte Chico that serves as the gateway to the Elqui Valley—one of Earth's clearest-skied locations, home to international observatories and traditional pisco distilleries. Must-dos include a pisco tasting tour followed by stargazing at a public observatory and visiting the Humboldt penguin reserve at Isla Damas. Clear skies prevail year-round, with winter (June-August) offering the best stargazing conditions.

San Antonio, Chile, Chile is a distinctive port city where deep cultural heritage meets authentic local atmosphere, featured on itineraries by Seabourn. Must-do experiences include walking the historic center to experience the layered architectural heritage, and seeking out the regional culinary traditions at a locally favored establishment away from the port area. The optimal time to visit is April through October, when warm weather and extended daylight create ideal conditions.