Fusina (Venice) to Rome (Civitavecchia)

Venice, approached from the Fusina port across its luminous lagoon, remains one of the world's most extraordinary cities — a thousand-year-old republic built on 118 islands and laced with canals, palaces, and masterpieces. Must-dos include riding the Grand Canal by vaporetto, savouring cicchetti at a traditional bacaro, and visiting the colourful islands of Murano and Burano. April through June and September through November offer the finest light and the most manageable crowds.

Split, Croatia's vibrant port city, is a unique blend of ancient history and modern life, centered around the remarkable Diocletian's Palace. Must-do experiences include savoring local dishes like pašticada and exploring the bustling markets. The best time to visit is during the spring and early fall, when the weather is pleasant and the tourist crowds are more manageable.

Dubrovnik, Croatia's stunning port city, is a blend of rich history, dramatic architecture, and vibrant culture, making it a must-visit destination. Don't miss a stroll along the city walls for breathtaking views and savor local dishes like "peka" and "black risotto." The best time to visit is in late spring or early fall when the weather is pleasant and the crowds are thinner.

Where Homer placed the island of the Phaeacians and four centuries of Venetian rule left their most enduring Mediterranean legacy, Corfu is a singular island of extraordinary historical depth and natural beauty. The UNESCO-listed Old Town — its narrow Kantounia alleyways, the elegant Liston arcade, and twin Venetian fortresses — is the finest preserved Venetian streetscape in Greece. Beyond the town, secret coves, olive groves of immense antiquity, and mountain villages offer weeks of unhurried discovery. May through June and September offer perfect conditions: warm sea temperatures, clear skies, and the island before or after its summer crescendo.

Argostoli is the capital of Kefalonia, the largest Ionian Island, renowned for dramatic geological wonders, pristine beaches, and the literary fame of Captain Corelli's Mandolin. Must-dos include visiting the subterranean Melissani Lake, admiring the cliffs of Myrtos Beach, and tasting Robola wine with fresh-grilled fish. May through October offers warm weather and calm seas, with June and September providing the best balance of conditions.

Monemvasia, a fortified port town on the Peloponnese, is celebrated for its medieval architecture and rich history dating back to the 6th century. Must-do experiences include savoring local dishes like **mpakaliaro** and exploring nearby attractions such as Nydri and Symi. The best time to visit is spring or early autumn when the weather is mild and the crowds are manageable.

The port that launched Athenian democracy's naval supremacy at the Battle of Salamis, Piraeus remains Greece's maritime heartbeat — and the most convenient gateway to both the Acropolis and the Aegean island chains. Dine on grilled sea bream at a Mikrolimano harbourside taverna, visit the extraordinary bronze Piraeus Apollo, and set sail for Hydra or Santorini by afternoon. Late April through June and September offer the Aegean at its most golden and uncrowded.

Valletta, Europe's smallest capital, is a fortress city of exceptional grandeur raised from bare limestone in just fifteen years after the Knights of St. John repelled the great Ottoman siege of 1565 — its rigid Renaissance grid of sun-drenched streets concealing a density of baroque palaces, gilded oratories, and subterranean World War II shelters unrivaled anywhere in the Mediterranean. The Grand Harbour, framed by golden bastions plunging into startlingly blue water, offers one of the most dramatically photogenic arrivals in the world for arriving vessels. Spring and autumn deliver the most comfortable temperatures for exploring this UNESCO-listed gem.

Palma de Mallorca announces itself with one of the most spectacular Gothic cathedrals in the world — La Seu, its honey-coloured sandstone buttresses rising directly from the bay, its interior modified by Antoni Gaudí and illuminated by the world's largest Gothic rose window. The old town behind it is a quarter of Arab baths, Renaissance palaces converted into boutique hotels, and the Passeig del Born — a plane-tree-shaded promenade where Balearic life conducts itself with unhurried grace. The local ensaïmada pastry and fresh sobrasada sausage from the island's black pigs are essential breakfast rituals. Visit May, June, or September: warm, brilliant, and measurably calmer than the July–August peak.

Barcelona is the city where Roman history, Gothic grandeur, and Gaudí's delirious Modernisme collide in a Mediterranean coastal capital of astonishing energy and beauty. The Sagrada Família — still under construction after 140 years — continues its audacious ascent toward completion, while the Gothic Quarter's Roman-era foundations and the Passeig de Gràcia's extraordinary concentration of Modernisme masterpieces reward days of exploration. For a complete sensory experience, lose an afternoon in the covered labyrinth of La Boqueria market before descending to the waterfront for Catalan seafood at its finest. May through June and September through October offer the most pleasant weather; the city connects directly to Paris by overnight train.

Palamós is an authentic Catalan fishing port on the Costa Brava, renowned for its legendary deep-water Gamba de Palamós red prawns and a vibrant working harbor where daily fish auctions continue centuries of maritime tradition. Must-dos include the Fishing Museum, coastal walks on the Camí de Ronda, and dining on fresh-from-the-sea Catalan cuisine. May through October offers ideal Mediterranean conditions.

Cannes, transformed from a sleepy Provençal fishing village into the Riviera's most glamorous resort by an English lord's chance quarantine in 1834, and immortalized by the Film Festival since 1946, remains the French Riviera's most theatrical stage — where La Croisette's curved promenade of Art Deco palaces, private beach clubs, and Palme d'Or dreams meets the quiet authenticity of the Suquet hilltop quarter above the old port. For shopping, the Marché Forville bursts with Provençal produce, truffle vendors, and cut flowers each morning; for dining, the restaurants of the old port district offer bouillabaisse and socca that need no red-carpet backdrop. Visit in spring or September; Nice is twenty minutes by rail and Monaco thirty.

Monaco, Monaco is a distinctive port city where deep cultural heritage meets authentic local atmosphere, featured on itineraries by Regent Seven Seas Cruises. Must-do experiences include walking the historic center to experience the layered architectural heritage, and seeking out the regional culinary traditions at a locally favored establishment away from the port area. The optimal time to visit is May through September, when mild temperatures and long days favor unhurried exploration.

Portofino is a jewel-box fishing village on Italy's Ligurian coast, renowned for its pastel harbour, Castello Brown fortress views, and exquisite pesto-dressed trofie pasta at waterside trattorias. Visitors should walk the coastal trail to the Cristo degli Abissi underwater statue at San Fruttuoso and savour focaccia di Recco with a glass of local Vermentino. The ideal season stretches from late April through October, with September offering the perfect balance of warm Mediterranean light and the intimate calm that returns after summer's peak.

Purpose-built as a Medici utopia in the late sixteenth century, Livorno was conceived from the outset as a city without discrimination — its founding Leggi Livornine granted equal rights to Jews, Christians, Muslims, and merchants of every nation, making it one of the most cosmopolitan cities in Renaissance Europe. Today, the Venetian-style canals of the Venezia Nuova quarter reflect colourful palazzi with a distinctly faded glamour, while the Mercato Centrale's fish counters display the cacciucco ingredients — a robust Livornese brodetto of five sea creatures — that make this port city a pilgrimage for serious eaters. Day trips to Pisa and Lucca are effortless from here. The season runs April through October.

Rome's ancient maritime gateway since the Emperor Trajan commissioned its harbour in 106 AD, Civitavecchia is the natural prologue to the Eternal City — just seventy minutes southeast by express rail. The port's Renaissance fortress, designed in part by Michelangelo, anchors a working waterfront that has welcomed travellers for millennia. Beyond Rome's unmissable monuments, consider an afternoon in the Civitavecchia thermal baths, drawing on mineral waters prized since antiquity. Spring and autumn offer the ideal balance of mild weather and manageable crowds for exploring the capital's layered history.