Civitavecchia (Rome) to Athens (Piraeus)

Rome's ancient maritime gateway since the Emperor Trajan commissioned its harbour in 106 AD, Civitavecchia is the natural prologue to the Eternal City — just seventy minutes southeast by express rail. The port's Renaissance fortress, designed in part by Michelangelo, anchors a working waterfront that has welcomed travellers for millennia. Beyond Rome's unmissable monuments, consider an afternoon in the Civitavecchia thermal baths, drawing on mineral waters prized since antiquity. Spring and autumn offer the ideal balance of mild weather and manageable crowds for exploring the capital's layered history.

Amalfi is the former maritime republic that gave its name to Italy's most celebrated coastline, where the Arab-Norman cathedral, medieval paper mills, and whitewashed buildings cascading to the Tyrrhenian Sea create the definitive image of Italian coastal beauty. Visit April through June via Windstar or Azamara for the Cloister of Paradise and the coastline that has been the world's standard for scenic perfection.

Reggio di Calabria is the toe of Italy's boot, home to the magnificent Bronzi di Riace bronze warriors and a sun-drenched waterfront promenade overlooking the Strait of Messina and Sicily. Must-dos include visiting the Magna Grecia museum, tasting 'nduja and grilled swordfish, and walking the Lungomare with Mount Etna in view. May through October offers the warmest weather and calmest strait conditions.

Catania is Sicily's dramatic second city, built from the black volcanic stone of Mount Etna and layered with Greek, Roman, and baroque heritage dating to 729 BC. Visitors should not miss the riotous Pescheria fish market and a tasting of authentic pasta alla Norma, followed by an excursion to the summit of Etna for views stretching to the Aeolian Islands. The best months to visit are April through June and September through October, when mild temperatures and thinner crowds allow the city's baroque streetscapes and extraordinary cuisine to be savored at a leisurely, unhurried pace.

Dubrovnik, Croatia's stunning port city, is a blend of rich history, dramatic architecture, and vibrant culture, making it a must-visit destination. Don't miss a stroll along the city walls for breathtaking views and savor local dishes like "peka" and "black risotto." The best time to visit is in late spring or early fall when the weather is pleasant and the crowds are thinner.

Rovinj, a historic port on Croatia's Istrian coast, is renowned for its medieval architecture, vibrant atmosphere, and delectable local cuisine. Be sure to savor dishes like **fuži** and **škampi na buzaru** while exploring its charming streets. The best time to visit is during the summer months when cultural festivals bring the town to life.

Venice, approached from the Fusina port across its luminous lagoon, remains one of the world's most extraordinary cities — a thousand-year-old republic built on 118 islands and laced with canals, palaces, and masterpieces. Must-dos include riding the Grand Canal by vaporetto, savouring cicchetti at a traditional bacaro, and visiting the colourful islands of Murano and Burano. April through June and September through November offer the finest light and the most manageable crowds.

Split, Croatia's vibrant port city, is a unique blend of ancient history and modern life, centered around the remarkable Diocletian's Palace. Must-do experiences include savoring local dishes like pašticada and exploring the bustling markets. The best time to visit is during the spring and early fall, when the weather is pleasant and the tourist crowds are more manageable.

The port of Kotor, a UNESCO World Heritage site, is renowned for its stunning natural beauty and rich historical tapestry. A must-do experience includes wandering the cobblestone streets of the Old Town, where culinary delights like "kacamak" and fresh seafood await. The best time to visit is during the spring or early fall, when the weather is pleasant and the crowds are fewer.

Where Homer placed the island of the Phaeacians and four centuries of Venetian rule left their most enduring Mediterranean legacy, Corfu is a singular island of extraordinary historical depth and natural beauty. The UNESCO-listed Old Town — its narrow Kantounia alleyways, the elegant Liston arcade, and twin Venetian fortresses — is the finest preserved Venetian streetscape in Greece. Beyond the town, secret coves, olive groves of immense antiquity, and mountain villages offer weeks of unhurried discovery. May through June and September offer perfect conditions: warm sea temperatures, clear skies, and the island before or after its summer crescendo.

Katakolon is the unassuming port that holds an extraordinary secret: just fourteen kilometres inland lies ancient Olympia, birthplace of the Olympic Games and one of the most sacred sites in the ancient world. The Archaeological Museum of Olympia — housing the breathtaking sculptures from the Temple of Zeus — ranks among Greece's finest, while walking the original stadium still sends a current of wonder through even the most seasoned traveller. The village itself charms with whitewashed tavernas and a relaxed pace that feels authentically Greek. Katakolon is best visited April through October; late spring and early autumn offer ideal temperatures for the Olympia excursion.

Santorini, the ancient volcanic caldera rising from the Aegean, is Greece's most theatrical landscape — a crescentic island of sheer white cliffs plunging into an indigo sea, its clifftop villages of Fira and Oia draped in bougainvillea and culminating in the world's most photographed sunset. The island's unique Assyrtiko wine, grown on ancient ungrafted vines in volcanic pumice, is one of the Mediterranean's greatest expressions of terroir. Byzantine frescoes of extraordinary beauty fill the Prehistoric Museum of Thera. The volcanic black and red sand beaches of Perissa and Perivolos are unlike any others in Greece. April through June and September through October offer the finest conditions.

The port that launched Athenian democracy's naval supremacy at the Battle of Salamis, Piraeus remains Greece's maritime heartbeat — and the most convenient gateway to both the Acropolis and the Aegean island chains. Dine on grilled sea bream at a Mikrolimano harbourside taverna, visit the extraordinary bronze Piraeus Apollo, and set sail for Hydra or Santorini by afternoon. Late April through June and September offer the Aegean at its most golden and uncrowded.