Romantic Rhine with 2 Nights in Lucerne (Northbound)

Cairo, where five thousand years of civilization press upon the present with relentless intensity, is anchored by the Great Pyramid of Giza — the sole survivor of the Seven Wonders of the Ancient World, already ancient when Cleopatra walked in its shadow. The Egyptian Museum's overwhelming treasure trove of pharaonic antiquities, including the golden mask of Tutankhamun, and the medieval labyrinth of Islamic Cairo, a UNESCO-listed district of a thousand mosques and medieval caravanserais, offer a lifetime of discovery in a city of twenty million souls. October through April brings the most tolerable temperatures. Luxor, with its Valley of the Kings, is a short domestic flight or overnight train journey south.

Framed by snowcapped Alps and the mirror-bright waters of Lake Lucerne, this medieval Swiss gem centres on the 14th-century Kapellbrücke — one of Europe's oldest covered bridges — and a colourful Altstadt that has changed little in five centuries. Ride the cog railway to cloud-wreathed Mount Pilatus, savour Älplermagronen in a timber-beamed tavern, and explore the nearby wonders of Interlaken and Grindelwald. Late spring through early autumn offers the most spectacular lake reflections and settled mountain weather.

Austria's third city has accomplished one of Europe's most convincing urban transformations — reinventing itself from industrial centre to cultural powerhouse, a journey recognised in 2009 when it was named European Capital of Culture. The Ars Electronica Center, a museum of digital art and technology that glows with LED light across the Danube each evening, epitomises Linz's forward-looking identity. Yet the city's Roman roots, its baroque Hauptplatz (one of Austria's finest main squares), and its proximity to the Wachau Valley anchor it firmly in history. The Upper Austrian cuisine — particularly Linzer Torte, the world's oldest-documented cake recipe — is exceptional. Linz is most agreeable May through September.

Cairo, where five thousand years of civilization press upon the present with relentless intensity, is anchored by the Great Pyramid of Giza — the sole survivor of the Seven Wonders of the Ancient World, already ancient when Cleopatra walked in its shadow. The Egyptian Museum's overwhelming treasure trove of pharaonic antiquities, including the golden mask of Tutankhamun, and the medieval labyrinth of Islamic Cairo, a UNESCO-listed district of a thousand mosques and medieval caravanserais, offer a lifetime of discovery in a city of twenty million souls. October through April brings the most tolerable temperatures. Luxor, with its Valley of the Kings, is a short domestic flight or overnight train journey south.

Luxor is the greatest open-air museum on earth — the modern city occupying the site of ancient Thebes, capital of Egypt during the New Kingdom's golden age when pharaohs such as Hatshepsut, Tutankhamun, and Ramesses II built temples of a scale and beauty that still stagger the imagination. The East Bank holds the incomparable complexes of Karnak and Luxor Temple; across the Nile, the West Bank conceals the Valley of the Kings, where sixty-three royal tombs were cut into the limestone beneath the pyramid-shaped peak of Al-Qurn. A felucca sunset sail on the Nile, with the cliffs of Thebes glowing amber, is among travel's most transcendent moments. October through April offers the ideal climate.

The Temple of Horus at Edfu is the most completely preserved pharaonic temple in Egypt — a colossus of golden sandstone rising above the Nile's western bank, its towering pylons, hypostyle halls, and sacred inner sanctum surviving almost intact after two millennia beneath the desert. Built between 237 and 57 BC under Ptolemaic rulers, it offers the clearest window into ancient Egyptian temple ritual that archaeology has preserved. The colossal granite statues of Horus at the entrance remain among the most striking sculptures of the ancient world. October through April brings ideal conditions: warm days, cool evenings, and the gentle rhythms of a Nile cruise.

Rüdesheim am Rhein, a jewel of the UNESCO-listed Upper Middle Rhine Valley, is where Germany's most storied wine river cuts through vine-terraced slopes and medieval castle ruins. The pedestrianised Drosselgasse laneway — beloved since the Romantic era — hums with wine taverns pouring the region's celebrated Rieslings, crisp and mineral from the slate soils. The Niederwald Monument surveys the river from the heights, reached by cable car above the vineyards. Day trips by boat unlock Bacharach, Boppard, and the legendary Lorelei rock. September's harvest festivals transform the entire valley into a convivial celebration of the vintage.

Aswan, Egypt's sunniest city and its ancient southern frontier, offers the Nile at its most scenic — wide, blue, and studded with felucca-dotted islands where temples emerge from the water's edge like visions from another age. The Temple of Philae, rescued from the rising waters of Lake Nasser and reassembled on a new island, is a jewel of Egyptian antiquity; Elephantine Island harbors ruins spanning predynastic times to the Roman era. For the full pharaonic experience, a sunset felucca ride to the Aga Khan Mausoleum rivals any luxury on the Nile. October through April offers the most comfortable temperatures; Abu Simbel is a short flight south.

Koblenz stands at the Deutsches Eck — the German Corner — where the Moselle river pours into the Rhine in a confluence so geographically commanding that the Romans built a fortress here in 9 BC. The result is a city of exceptional Rhine Gorge scenery, with the formidable Ehrenbreitstein Fortress, one of Europe's largest, crowning the opposite bank and reachable by gondola for panoramas that stretch across three river valleys. A Rhine wine tasting at one of the city's historic Weinstuben, followed by a stroll through the Altstadt's baroque squares, is the definitive Koblenz afternoon. The finest weather arrives April through October, with the Rhine in Flames fireworks festival in August being particularly spectacular.