From the Inca Empire to the Peruvian Amazon with Galápagos Cruise

Lisbon, Portugal's enchanting capital, stands out for its rich history, stunning architecture, and vibrant culture. Must-try experiences include savoring local dishes like bacalhau à brás and pastéis de nata at Mercado da Ribeira. The best time to visit is during the spring or fall, when the weather is mild and the city is alive with festivals and events.

Lisbon, Portugal's enchanting capital, stands out for its rich history, stunning architecture, and vibrant culture. Must-try experiences include savoring local dishes like bacalhau à brás and pastéis de nata at Mercado da Ribeira. The best time to visit is during the spring or fall, when the weather is mild and the city is alive with festivals and events.

Novi Sad — the "Serbian Athens" — unfolds along the left bank of the Danube beneath the commanding walls of the Petrovaradin Fortress, a Habsburg military masterpiece whose underground tunnel labyrinth and hilltop clock tower (with hands reversed, to confuse enemy gunners) make for one of Europe's most unusual fortress visits. The city's elegant pedestrian street, the Zmaj Jovina, is lined with 19th-century Habsburg architecture that rewards a leisurely afternoon, while the Serbian cultural renaissance of the same era left behind museums, galleries, and coffee house traditions that endure today. In July, the EXIT music festival transforms the fortress into one of Europe's most storied outdoor stages. Visit May through September for the finest weather.

Porto, set dramatically on the granite bluffs above the Douro River, is among Europe's most romantically dishevelled cities — a place where baroque church towers rise above terracotta rooftops and century-old azulejo tilework lines every alley. Cross the iron Dom Luís I Bridge for sweeping views and descend into Vila Nova de Gaia's atmospheric wine lodges for a tasting of aged tawny port direct from the barrel. Seafood is magnificent: salt cod prepared a hundred ways, barnacles glistening with lemon, and custard tarts still warm from the oven. Spring and early autumn offer the finest conditions.

Régua, gateway to Portugal's vertiginous Douro Valley wine country, sits at the point where the river enters its most dramatic gorge — terraced vineyards climbing impossible slopes on every side, their schist walls a testament to generations of viticultural determination. The Wine Museum in Pinhão's art nouveau azulejo station captures the region's soul, while the great quintas — Ramos Pinto, Croft, Niepoort — open their cellars for intimate tastings of vintage port and luminous dry whites. Harvest season in September and October transforms the valley into a festival of colour and ferment.

Cusco is the former Inca capital at 3,399 meters in the Peruvian Andes, where precisely fitted Inca stonework supports Spanish colonial churches in a city that is the gateway to Machu Picchu and one of South America's most exciting culinary destinations. Must-dos include exploring the Plaza de Armas and its twin cathedrals, visiting Sacsayhuamán fortress, and dining on cuy and alpaca with Andean superfoods. Visit May to October for dry weather, with June for the Inti Raymi festival.

The port of Lima is a vibrant gateway to Peru's rich history and culinary excellence, making it a must-visit destination for travelers. Savor local delicacies like ceviche and explore nearby attractions such as the coastal district of Callao and the breathtaking landscapes of Puno. The best time to visit is during the dry season from May to September, when the weather is ideal for exploration.

Iquitos, the world’s largest city unreachable by road, sits on the Peruvian Amazon amid rubber-boom mansions and serves as the gateway to some of Earth’s most biodiverse rainforest. Must-dos include exploring Pacaya-Samiria’s flooded forests for pink dolphins, browsing the Belén market’s Amazonian ingredients, and tasting paiche ceviche. Visit June through October for low-water wildlife concentration, or December through May for canoe exploration of the flooded forest.

Nauta, Peru, delivers South America's irresistible combination of dramatic landscapes, vibrant culture, and extraordinary biodiversity. Essential experiences include exploring local markets, tasting the distinctive regional cuisine, and venturing into the surrounding natural environments. Best visited year-round, though the drier months from May to October tend to offer the most comfortable conditions. Cruise lines including Uniworld River Cruises feature this port on their most compelling itineraries. Whether you have a few hours or a full day, the port rewards exploration at every pace and in every direction.

Pocinho marks the easternmost navigable point of the Douro River — the terminus of the valley where port wine's history began and where the landscape reaches its most elemental and dramatic expression: near-vertical schist slopes terraced into vineyard stairways, the river running silver between them in the early morning light. The restored rabelo boats that once carried casks of wine downriver are now a romanticised memory, but the valley's working quintas welcome visitors for tastings of the upper Douro's increasingly celebrated unfortified wines. The Douro International Natural Park, bordering Spain, protects rare Egyptian vulture colonies on the surrounding plateau. September through October, during harvest, is the unmissable season.

Barca d'Alva, a remote frontier village at the uppermost navigable point of the Douro River, marks the eastern terminus of Portuguese river cruises where the landscape shifts from terraced port wine vineyards into the austere granite borderlands of Trás-os-Montes. The abandoned azulejo-tiled railway station, the almond orchards cascading to the river's edge, and the silence of the surrounding Côa Valley archaeological park — protecting the world's most important collection of open-air Palaeolithic rock art — make this an unexpectedly rich stopping point. Spring brings almond blossom along every hillside; autumn arrives golden with the vendange harvest. The Spanish city of Salamanca lies an hour's drive east.