Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound)

Lake Como, Italy is a distinctive port city where deep cultural heritage meets authentic local atmosphere, featured on itineraries by Uniworld River Cruises. Must-do experiences include walking the historic center to experience the layered architectural heritage, and seeking out the regional culinary traditions at a locally favored establishment away from the port area. The optimal time to visit is May through September, when mild temperatures and long days favor unhurried exploration.

Cairo, where five thousand years of civilization press upon the present with relentless intensity, is anchored by the Great Pyramid of Giza — the sole survivor of the Seven Wonders of the Ancient World, already ancient when Cleopatra walked in its shadow. The Egyptian Museum's overwhelming treasure trove of pharaonic antiquities, including the golden mask of Tutankhamun, and the medieval labyrinth of Islamic Cairo, a UNESCO-listed district of a thousand mosques and medieval caravanserais, offer a lifetime of discovery in a city of twenty million souls. October through April brings the most tolerable temperatures. Luxor, with its Valley of the Kings, is a short domestic flight or overnight train journey south.

Lake Como, Italy is a distinctive port city where deep cultural heritage meets authentic local atmosphere, featured on itineraries by Uniworld River Cruises. Must-do experiences include walking the historic center to experience the layered architectural heritage, and seeking out the regional culinary traditions at a locally favored establishment away from the port area. The optimal time to visit is May through September, when mild temperatures and long days favor unhurried exploration.

Framed by snowcapped Alps and the mirror-bright waters of Lake Lucerne, this medieval Swiss gem centres on the 14th-century Kapellbrücke — one of Europe's oldest covered bridges — and a colourful Altstadt that has changed little in five centuries. Ride the cog railway to cloud-wreathed Mount Pilatus, savour Älplermagronen in a timber-beamed tavern, and explore the nearby wonders of Interlaken and Grindelwald. Late spring through early autumn offers the most spectacular lake reflections and settled mountain weather.

Breisach am Rhein clings to a volcanic hilltop at the French-German border, commanding the Upper Rhine crossing that made it one of the most fought-over towns in European history — a past the Romanesque-Gothic Münster St. Stephan surveys serenely from its commanding heights. Today peace reigns, and Breisach's true gift is its position as a gateway to three celebrated wine regions: the German Kaiserstuhl, producing some of Germany's finest Spätburgunder; the French Alsace, just across the Rhine; and the rolling hills of the Baden wine country to the east. Visit in autumn for harvest season across all three regions simultaneously. Freiburg im Breisgau, the Black Forest's graceful capital, lies twenty minutes east.

Sitting directly across the Rhine from Strasbourg, Kehl offers Rhine river cruise guests the remarkable experience of crossing from Germany into France in five minutes on foot — arriving at a medieval Alsatian cathedral quarter whose tarte flambée, Riesling estates, and half-timbered Petite France canals represent some of Europe's most enduring pleasures. The surrounding Black Forest and Alsatian Wine Route extend the discovery. Spring blossoms and autumn harvest are the most atmospheric times to visit this Franco-German frontier town.

Mainz is where the modern world was printed into existence: Johannes Gutenberg's invention of movable-type printing around 1440 transformed this ancient Rhine city into the birthplace of the information age, a legacy honoured at the extraordinary Gutenberg Museum, home to one of the surviving original Bibles. The Romanesque cathedral of St. Martin, built over a millennium from the year 975, anchors a charming old town of wine taverns and market squares where Rhenish Rieslings flow freely. Visit between spring and autumn for the famous Mainz Wine Market held beside the Rhine. A day-cruise port with surprising cultural depth.

Aswan, Egypt's sunniest city and its ancient southern frontier, offers the Nile at its most scenic — wide, blue, and studded with felucca-dotted islands where temples emerge from the water's edge like visions from another age. The Temple of Philae, rescued from the rising waters of Lake Nasser and reassembled on a new island, is a jewel of Egyptian antiquity; Elephantine Island harbors ruins spanning predynastic times to the Roman era. For the full pharaonic experience, a sunset felucca ride to the Aga Khan Mausoleum rivals any luxury on the Nile. October through April offers the most comfortable temperatures; Abu Simbel is a short flight south.